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Optimum Operation Point Measurements and Data Postprocessing of a Bearingless Spinfilter
In this project, you will conduct measurements of a bearingless spinfilter prototype with state-of-the-art equipment of the industry partner under different conditions. The measurement data will be processed to find the optimum operation point and you will conduct an error caluclation.
At HPE, a levitating spinfilter with bearingless electric motors is developed
for ultra-clean applications as required in the pharmaceutical industry. The
rotation of the filter membrane generates a tangential flow, which keeps the
membrane clean. However, due to the centrifugal pressure from within the
filter membrane, the transmembrane pressure is reduced at high rotational
speeds. Additionally, time-variant fouling, particle-membrane interactions
and cell damage play a crucial role, which is difficult to predict.
During your project, you will setup and conduct multiple measurement
series with different cell suspensions under various operational conditions of
the spinfilter prototype in the laboratories of the industry partner in Zurich
Altstetten. You will then process your measurement data and calculate the
error propagation. In this project, you have the opportunity to get handson
experience with state-of-the-art equipment in a professional biotech
laboratory.
At HPE, a levitating spinfilter with bearingless electric motors is developed for ultra-clean applications as required in the pharmaceutical industry. The rotation of the filter membrane generates a tangential flow, which keeps the membrane clean. However, due to the centrifugal pressure from within the filter membrane, the transmembrane pressure is reduced at high rotational speeds. Additionally, time-variant fouling, particle-membrane interactions and cell damage play a crucial role, which is difficult to predict. During your project, you will setup and conduct multiple measurement series with different cell suspensions under various operational conditions of the spinfilter prototype in the laboratories of the industry partner in Zurich Altstetten. You will then process your measurement data and calculate the error propagation. In this project, you have the opportunity to get handson experience with state-of-the-art equipment in a professional biotech laboratory.
Lars Beglinger, beglinger@hpe.ee.ethz.ch
Lars Beglinger, beglinger@hpe.ee.ethz.ch
20% Implementation
20% Modelling
50% Testing
10% Theory
20% Implementation 20% Modelling 50% Testing 10% Theory
Accurate work in the lab, Working language: English/German
Accurate work in the lab, Working language: English/German