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Assembling an advanced high-speed SICM for live cell imaging
Scanning ion conductance microscopy (SICM) is the non-contact SPM technology to image live cells based on glass capillaries with a nanometric aperture. It applies a voltage and measures the ionic current flowing through the pipette above the sample in the buffer solution: the recorded current represents the feedback signal to measure the topography of the sample. In collaboration with Prof. Fantner at EPFL, this project aims to assemble a state of the art high-speed SICM to enable time-resolved live cell imaging.
Keywords: high-speed SICM, live cell imaging, control, electronics, FPGA, and data analysis
Under the existing hs-SICM frame, you have the opportunity to be directly involved in the assembling the hardware of a new SICM, the improvement of the advanced data-driven controller (FPGA), the PCB board fabrication, the data analysis and noise analysis. You will characterize the assembled hs-SCIM for live cell imaging. The scope of the project can be adapted to fit your background. The start date is flexible. The project can be tailored to individual subprojects to fit personal preference.
If you, a student with the corresponding skills OR willingly to learn, are interested, please, just send me an email (xumen@ethz.ch) to briefly introduce yourself. Thank you!
Under the existing hs-SICM frame, you have the opportunity to be directly involved in the assembling the hardware of a new SICM, the improvement of the advanced data-driven controller (FPGA), the PCB board fabrication, the data analysis and noise analysis. You will characterize the assembled hs-SCIM for live cell imaging. The scope of the project can be adapted to fit your background. The start date is flexible. The project can be tailored to individual subprojects to fit personal preference.
If you, a student with the corresponding skills OR willingly to learn, are interested, please, just send me an email (xumen@ethz.ch) to briefly introduce yourself. Thank you!
To assemble a hs-SICM for live cell imaging
To assemble a hs-SICM for live cell imaging
Laboratory of Biosensors and Bioelectronics (LBB)
Mengjia Xu
xumen@ethz.ch
Laboratory of Biosensors and Bioelectronics (LBB) Mengjia Xu xumen@ethz.ch